Hepatic Venous Pressure Gradient

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Hepatic venous pressure gradient: clinical use in chronic liver disease

Portal hypertension is a severe consequence of chronic liver diseases and is responsible for the main clinical complications of liver cirrhosis. Hepatic venous pressure gradient (HVPG) measurement is the best available method to evaluate the presence and severity of portal hypertension. Clinically significant portal hypertension is defined as an increase in HVPG to >10 mmHg. In this condition, ...

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Hepatic venous pressure gradient measurement: time to learn!

Portal hypertension is a clinical syndrome defined by a pathological increase in portal pressure. The development of cirrhosis of the liver is characterized by clinical manifestations related to portal hypertension like esophageal varices, ascites, bleeding, and encephalopathy. Direct measurement of portal pressure is invasive, inconvenient, and clinically impractical. Currently, the most commo...

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Minimal Hepatic Encephalopathy in Patients with Cirrhosis by Measuring Liver Stiffness and Hepatic Venous Pressure Gradient

BACKGROUND/AIM Transient elastography (TE) of liver and hepatic venous pressure gradient (HVPG) allows accurate prediction of cirrhosis and its complications in patients with chronic liver disease. There is no study on prediction of minimal hepatic encephalopathy (MHE) using TE and HVPG in patients with cirrhosis. PATIENTS AND METHODS Consecutive cirrhotic patients who never had an episode of...

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Cost-effectiveness of hepatic venous pressure gradient measurements for prophylaxis of variceal re-bleeding.

BACKGROUND Measurement of the hepatic venous pressure gradient may identify a sub-optimal response to drug prophylaxis in patients with a history of variceal bleeding. However, the cost-effectiveness of routine hepatic venous pressure gradient measurements to guide secondary prophylaxis has not been examined. METHODS A Markov model was constructed using specialized software (DATA 3.5, William...

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Are there any alternative methods to hepatic venous pressure gradient in portal hypertension assessment?

Portal hypertension is a major consequence of any chronic liver disease and it represents the main mechanism of complication occurrence. Therefore, the assessment of portal hypertension presence is one of the most important steps in the management of any chronic liver diseases. The most accurate tool for portal pressure assessment is hepatic venous pressure gradient (HVPG) measurement, which ha...

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ژورنال

عنوان ژورنال: Clinical Liver Disease

سال: 2021

ISSN: 2046-2484,2046-2484

DOI: 10.1002/cld.1031